The Berkeley River is a river in the Kimberley region of Western Australia.
The river flows for 135 km to the Timor Sea via the Joseph Bonaparte Gulf near Reveley Island and Cape St Lambert.
The river rises from the Tadrida Scarp and flows in a north-easterly direction through the Drysdale River National Park and the Oombulgarri Indigenous Reserve before discharging into the Timor Sea. The river has two tributaries, the De Lancourt River and Casuarina Creek.
