Großer Labussee is a lake in the Mecklenburg Lake District, in Germany. It is situated in the district of Mecklenburgische Seenplatte of the state of Mecklenburg-Vorpommern. Most of the lake is in the municipality Userin, with a small southern part in the municipality Wesenberg.
The lake has an elevation of 57.5 metres and its surface area is 3.3 square kilometres.
